Publikationen des SFB1035 von 2013

A10: Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity.
Gross Stefan, Nguyen Fabian, Bierschenk Matthias, Sohmen Daniel, Menzel Thomas, Antes Iris, Wilson Daniel N., Bach Thorsten
ChemMedChem. 2013 Dec 8
doi: 10.1002/cmdc.201300323


B03: Studying weak and dynamic interactions of posttranslationally modified proteins using expressed protein ligation.
Tripsianes Konstantinos, Chu Nam K., Friberg Anders, Sattler Michael, Becker Christian F. W.
ACS Chem Biol. 2013 Dec 6 
doi: 10.1021/cb400723j


B03: Structural features of Argonaute-GW182 protein interactions.
Pfaff Janina, Hennig Janosch, Herzog Franz, Aebersold Ruedi, Sattler Michael, Niessing Dierk, Meister Gunter
Proc Natl Acad Sci USA. 2013 Oct 1 
doi: 10.1073/pnas.1308510110


A01: Opening windows into the cell: focused-ion-beam milling for cryo-electron tomography.
Villa Elizabeth, Schaffer Miroslava, Plitzko Jürgen M., Baumeister Wolfgang
Curr Opin Struct Biol. 2013 Oct 
doi: 10.1016/


B03: Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.
Dallmann Andre, Simon Bernd, Duszczyk Malgorzata M., Kooshapur Hamed, Pardi Arthur, Bermel Wolfgang, Sattler Michael
Angew Chem Int Ed Engl. 2013 Sep 27 
doi: 10.1002/anie.201304391


B05: Intermediates in the guanine nucleotide exchange reaction of Rab8 catalyzed by Rabin8/GRAB.
Guo Zhong, Hou Xiaomin, Goody Roger S., Itzen Aymelt
J Biol Chem. 2013 Sep 26 
doi: 10.1074/jbc.M113.498329


B06: Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Aβ40.
Yan Li-Mei, Velkova Aleksandra, Tatarek-Nossol Marianna, Rammes Gerhard, Sibaev Andrei, Andreetto Erika, Kracklauer Michael, Bakou Maria, Malideli Eleni, Göke Burkhard, Schirra Jörg, Storr Martin, Kapurniotu Aphrodite
Angew Chem Int Ed Engl. 2013 Sep 23 
doi: 10.1002/anie.201302840


B07/B03: Proton-detected solid-state NMR spectroscopy at aliphatic sites: application to crystalline systems.
Asami Sam, Reif Bernd
Acc Chem Res. 2013 Sep 17 
doi: 10.1021/ar400063y


A06: Regulated structural transitions unleash the chaperone activity of αB-crystallin.
Peschek Jirka, Braun Nathalie, Rohrberg Julia, Back Katrin Christiane, Kriehuber Thomas, Kastenmüller Andreas, Weinkauf Sevil, Buchner Johannes
Proc Natl Acad Sci USA. 2013 Sep 16 
doi: 10.1073/pnas.1308898110


A04: Quantification of interaction strengths between chaperones and tetratricopeptide repeat domain containing membrane proteins.
Schweiger Regina, Soll Jürgen, Jung Kirsten, Heermann Ralf, Schwenkert Serena
J Biol Chem 2013 Sep 13 
doi: 10.1074/jbc.M113.493015


B05: Activation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infection.
Rothmeier Eva, Pfaffinger Gudrun, Hoffmann Christine, Harrison Christopher F., Grabmayr Heinrich, Repnik Urska, Hannemann Mandy, Wölke Stefan, Bausch Andreas, Griffiths Gareth, Müller-Taubenberger Annette, Itzen Aymelt, Hilbi Hubert
PLoS Pathog. 2013 Sep 9
doi: 10.1371/journal.ppat.1003598


A01: Unveiling the long-held secrets of the 26S proteasome.
Förster Friedrich, Unverdorben Pia, Sledź Paweł, Baumeister Wolfgang
Structure. 2013 Sep 3 
doi: 10.1016/j.str.2013.08.010


B07: Hydrogen bonding involving side chain exchangeable groups stabilizes amyloid quarternary structure.
Agarwal Vipin, Linser Rasmus, Dasari Muralidhar, Fink Uwe, Lopez del Amo Juan Miguel, Reif Bernd
Phys Chem Chem Phys. 2013 Aug 14 
doi: 10.1039/c3cp44653k


B07: NMR spectroscopy of soluble protein complexes at one mega-dalton and beyond.
Mainz Andi, Religa Tomasz L., Sprangers Remco, Linser Rasmus, Kay Lewis E., Reif Bernd
Angew Chem Int Ed Engl. 2013 Aug 12 
doi: 10.1002/anie.201301215


A07: Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions.
Sharif Humayun, Özgür Sevim, Sharma Kundan, Basquin Claire, Urlaub Henning, Conti Elena
Nucleic Acids Res. 2013 Jul 12 


A09/A02: Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad.
Zeiler Evelyn, List Anja, Alte Ferdinand, Gersch Malte, Wachtel Rudolf, Poreba Marcin, Drag Marcin, Groll Michael, Sieber Stephan A.
Proc Natl Acad Sci USA. 2013 Jul 9 
doi: 10.1073/pnas.1219125110


A07: Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
von Moeller Holger, Lerner Rachel, Ricciardi Adele, Basquin Claire, Marzluff William F., Conti Elena
Nucleic Acids Res. 2013 Jun 26 


A04: AtTPR7 as part of the Arabidopsis Sec post-translocon.
Schweiger Regina, Schwenkert Serena
Plant Signal Behav. 2013 Jun 11 
doi: 10.4161/psb.25286


A01: Localization of the regulatory particle subunit Sem1 in the 26S proteasome.
Bohn Stefan, Sakata Eri, Beck Florian, Pathare Ganesh R., Schnitger Jérôme, Nágy Istvan, Baumeister Wolfgang, Förster Friedrich
Biochem Biophys Res Commun. 2013 May 31 
doi: 10.1016/j.bbrc.2013.04.069


A11: Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET.
Sikor Martin, Mapa Koyeli, Voith von Voithenberg Lena, Mokranjac Dejana, Lamb Don C.
EMBO J. 2013 May 29 
doi: 10.1038/emboj.2013.89


A01: Allosteric effects in the regulation of 26S proteasome activities.
Sledź Paweł, Förster Friedrich, Baumeister Wolfgang
J Mol Biol. 2013 May 13 
doi: 10.1016/j.jmb.2013.01.036


A01: Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation.
Sledź Paweł, Unverdorben Pia, Beck Florian, Pfeifer Günter, Schweitzer Andreas, Förster Friedrich, Baumeister Wolfgang
Proc Natl Acad Sci USA. 2013 Apr 30 
doi: 10.1073/pnas.1305782110


B03: Translational repression of thymidylate synthase by targeting its mRNA.
Garg Divita , Beribisky Alexander V., Ponterini Glauco, Ligabue Alessio, Marverti Gaetano, Martello Andrea, Costi M. Paola, Sattler Michael, Wade Rebecca C.
Nucleic Acids Res. 2013 Apr 
doi: 10.1093/nar/gkt098


A07: Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
Makino Debora Lika, Baumgärtner Marc, Conti Elena
Nature. 2013 Mar 7 
doi: 10.1038/nature11870


A09: The mechanism of Caseinolytic (ClpP) protease inhibition.
Gersch Malte, Gut Felix, Korotkov Vadim S., Lehmann Johannes, Böttcher Thomas, Rusch Marion, Hedberg Christian, Waldmann Herbert, Klebe Gerhard, Sieber Stephan A.
Angew Chem Int Ed Engl. 2013 Mar 4 
doi: 10.1002/anie.201204690


B03: Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex.
Hennig Janosch, Wang Iren, Sonntag Miriam, Gabel Frank, Sattler Michael
J Biomol NMR. 2013 Mar 3 
doi: 10.1007/s10858-013-9719-9


A03: Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle.
Li Jing, Richter Klaus, Reinstein Jochen, Buchner Johannes
Nat Struct Mol Biol. 2013 Mar 
doi: 10.1038/nsmb.2502


B02: Role of tyrosine hot-spot residues at the interface of colicin E9 and immunity protein 9: a comparative free energy simulation study.
Luitz Manuel P., Zacharias Martin
Proteins. 2013 Mar 
doi: 10.1002/prot.24203


B07/B03: Protein–RNA interfaces probed by 1H-detected MAS solid-state NMR spectroscopy.
Asami Sam, Rakwalska-Bange Magdalena, Carlomagno Teresa, Reif Bernd
Angew Chem Int Ed Engl. 2013 Feb 18 
doi: 10.1002/anie.201208024


B05: Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.
Gazdag Emerich Mihai, Streller Alexandra, Haneburger Ina, Hilbi Hubert, Vetter Ingrid R., Goody Roger S., Itzen Aymelt
EMBO Rep. 2013 Feb 
doi: 10.1038/embor.2012.211


A05: Force as a single molecule probe of multidimensional protein energy landscapes.
Zoldák Gabriel, Rief Matthias
Curr Opin Struct Biol. 2013 Feb 
doi: 10.1016/


B03/A09: Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 30-splice site recognition.
Zhang Yun, Madl Tobias, Bagdiul Ivona, Kern Thomas, Kang Hyun-Seo, Zou Peijian, Mäusbacher Nina, Sieber Stephan A., Krämer Angela, Sattler Michael
Nucleic Acids Res. 2013 Jan 
doi: 10.1093/nar/gks1097