Publikationen des SFB1035 von 2013

A10: Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity.
^{Gross Stefan, Nguyen Fabian, Bierschenk Matthias, Sohmen Daniel, Menzel Thomas, Antes Iris, Wilson Daniel N., Bach Thorsten}
ChemMedChem. 2013 Dec 8
doi: 10.1002/cmdc.201300323

 

B03: Studying weak and dynamic interactions of posttranslationally modified proteins using expressed protein ligation.
^{Tripsianes Konstantinos, Chu Nam K., Friberg Anders, Sattler Michael, Becker Christian F. W.}
ACS Chem Biol. 2013 Dec 6 
doi: 10.1021/cb400723j

 

B03: Structural features of Argonaute-GW182 protein interactions.
^{Pfaff Janina, Hennig Janosch, Herzog Franz, Aebersold Ruedi, Sattler Michael, Niessing Dierk, Meister Gunter}
Proc Natl Acad Sci USA. 2013 Oct 1 
doi: 10.1073/pnas.1308510110

 

A01: Opening windows into the cell: focused-ion-beam milling for cryo-electron tomography.
^{Villa Elizabeth, Schaffer Miroslava, Plitzko Jürgen M., Baumeister Wolfgang}
Curr Opin Struct Biol. 2013 Oct 
doi: 10.1016/j.sbi.2013.08.006

 

B03: Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.
^{Dallmann Andre, Simon Bernd, Duszczyk Malgorzata M., Kooshapur Hamed, Pardi Arthur, Bermel Wolfgang, Sattler Michael}
Angew Chem Int Ed Engl. 2013 Sep 27 
doi: 10.1002/anie.201304391

 

B05: Intermediates in the guanine nucleotide exchange reaction of Rab8 catalyzed by Rabin8/GRAB.
^{Guo Zhong, Hou Xiaomin, Goody Roger S., Itzen Aymelt}
J Biol Chem. 2013 Sep 26 
doi: 10.1074/jbc.M113.498329

 

B06: Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Aβ40.
^{Yan Li-Mei, Velkova Aleksandra, Tatarek-Nossol Marianna, Rammes Gerhard, Sibaev Andrei, Andreetto Erika, Kracklauer Michael, Bakou Maria, Malideli Eleni, Göke Burkhard, Schirra Jörg, Storr Martin, Kapurniotu Aphrodite}
Angew Chem Int Ed Engl. 2013 Sep 23 
doi: 10.1002/anie.201302840

 

B07/B03: Proton-detected solid-state NMR spectroscopy at aliphatic sites: application to crystalline systems.
^{Asami Sam, Reif Bernd}
Acc Chem Res. 2013 Sep 17 
doi: 10.1021/ar400063y

 

A06: Regulated structural transitions unleash the chaperone activity of αB-crystallin.
^{Peschek Jirka, Braun Nathalie, Rohrberg Julia, Back Katrin Christiane, Kriehuber Thomas, Kastenmüller Andreas, Weinkauf Sevil, Buchner Johannes}
Proc Natl Acad Sci USA. 2013 Sep 16 
doi: 10.1073/pnas.1308898110

 

A04: Quantification of interaction strengths between chaperones and tetratricopeptide repeat domain containing membrane proteins.
^{Schweiger Regina, Soll Jürgen, Jung Kirsten, Heermann Ralf, Schwenkert Serena}
J Biol Chem 2013 Sep 13 
doi: 10.1074/jbc.M113.493015

 

B05: Activation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infection.
^{Rothmeier Eva, Pfaffinger Gudrun, Hoffmann Christine, Harrison Christopher F., Grabmayr Heinrich, Repnik Urska, Hannemann Mandy, Wölke Stefan, Bausch Andreas, Griffiths Gareth, Müller-Taubenberger Annette, Itzen Aymelt, Hilbi Hubert}
PLoS Pathog. 2013 Sep 9
doi: 10.1371/journal.ppat.1003598

 

A01: Unveiling the long-held secrets of the 26S proteasome.
^{Förster Friedrich, Unverdorben Pia, Sledź Paweł, Baumeister Wolfgang}
Structure. 2013 Sep 3 
doi: 10.1016/j.str.2013.08.010

 

B07: Hydrogen bonding involving side chain exchangeable groups stabilizes amyloid quarternary structure.
^{Agarwal Vipin, Linser Rasmus, Dasari Muralidhar, Fink Uwe, Lopez del Amo Juan Miguel, Reif Bernd}
Phys Chem Chem Phys. 2013 Aug 14 
doi: 10.1039/c3cp44653k

 

B07: NMR spectroscopy of soluble protein complexes at one mega-dalton and beyond.
^{Mainz Andi, Religa Tomasz L., Sprangers Remco, Linser Rasmus, Kay Lewis E., Reif Bernd}
Angew Chem Int Ed Engl. 2013 Aug 12 
doi: 10.1002/anie.201301215

 

A07: Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions.
^{Sharif Humayun, Özgür Sevim, Sharma Kundan, Basquin Claire, Urlaub Henning, Conti Elena}
Nucleic Acids Res. 2013 Jul 12 
doi:10.1093/nar/gkt600

 

A09/A02: Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad.
^{Zeiler Evelyn, List Anja, Alte Ferdinand, Gersch Malte, Wachtel Rudolf, Poreba Marcin, Drag Marcin, Groll Michael, Sieber Stephan A.}
Proc Natl Acad Sci USA. 2013 Jul 9 
doi: 10.1073/pnas.1219125110

 

A07: Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
^{von Moeller Holger, Lerner Rachel, Ricciardi Adele, Basquin Claire, Marzluff William F., Conti Elena}
Nucleic Acids Res. 2013 Jun 26 
doi:10.1093/nar/gkt558

 

A04: AtTPR7 as part of the Arabidopsis Sec post-translocon.
^{Schweiger Regina, Schwenkert Serena}
Plant Signal Behav. 2013 Jun 11 
doi: 10.4161/psb.25286

 

A01: Localization of the regulatory particle subunit Sem1 in the 26S proteasome.
^{Bohn Stefan, Sakata Eri, Beck Florian, Pathare Ganesh R., Schnitger Jérôme, Nágy Istvan, Baumeister Wolfgang, Förster Friedrich}
Biochem Biophys Res Commun. 2013 May 31 
doi: 10.1016/j.bbrc.2013.04.069

 

A11: Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET.
^{Sikor Martin, Mapa Koyeli, Voith von Voithenberg Lena, Mokranjac Dejana, Lamb Don C.}
EMBO J. 2013 May 29 
doi: 10.1038/emboj.2013.89

 

A01: Allosteric effects in the regulation of 26S proteasome activities.
^{Sledź Paweł, Förster Friedrich, Baumeister Wolfgang}
J Mol Biol. 2013 May 13 
doi: 10.1016/j.jmb.2013.01.036

 

A01: Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation.
^{Sledź Paweł, Unverdorben Pia, Beck Florian, Pfeifer Günter, Schweitzer Andreas, Förster Friedrich, Baumeister Wolfgang}
Proc Natl Acad Sci USA. 2013 Apr 30 
doi: 10.1073/pnas.1305782110

 

B03: Translational repression of thymidylate synthase by targeting its mRNA.
^{Garg Divita , Beribisky Alexander V., Ponterini Glauco, Ligabue Alessio, Marverti Gaetano, Martello Andrea, Costi M. Paola, Sattler Michael, Wade Rebecca C.}
Nucleic Acids Res. 2013 Apr 
doi: 10.1093/nar/gkt098

 

A07: Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
^{Makino Debora Lika, Baumgärtner Marc, Conti Elena}
Nature. 2013 Mar 7 
doi: 10.1038/nature11870

 

A09: The mechanism of Caseinolytic (ClpP) protease inhibition.
^{Gersch Malte, Gut Felix, Korotkov Vadim S., Lehmann Johannes, Böttcher Thomas, Rusch Marion, Hedberg Christian, Waldmann Herbert, Klebe Gerhard, Sieber Stephan A.}
Angew Chem Int Ed Engl. 2013 Mar 4 
doi: 10.1002/anie.201204690

 

B03: Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex.
^{Hennig Janosch, Wang Iren, Sonntag Miriam, Gabel Frank, Sattler Michael}
J Biomol NMR. 2013 Mar 3 
doi: 10.1007/s10858-013-9719-9

 

A03: Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle.
^{Li Jing, Richter Klaus, Reinstein Jochen, Buchner Johannes}
Nat Struct Mol Biol. 2013 Mar 
doi: 10.1038/nsmb.2502

 

B02: Role of tyrosine hot-spot residues at the interface of colicin E9 and immunity protein 9: a comparative free energy simulation study.
^{Luitz Manuel P., Zacharias Marti}n
Proteins. 2013 Mar 
doi: 10.1002/prot.24203

 

B07/B03: Protein–RNA interfaces probed by 1H-detected MAS solid-state NMR spectroscopy.
^{Asami Sam, Rakwalska-Bange Magdalena, Carlomagno Teresa, Reif Bernd}
Angew Chem Int Ed Engl. 2013 Feb 18 
doi: 10.1002/anie.201208024

 

B05: Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.
^{Gazdag Emerich Mihai, Streller Alexandra, Haneburger Ina, Hilbi Hubert, Vetter Ingrid R., Goody Roger S., Itzen Aymelt}
EMBO Rep. 2013 Feb 
doi: 10.1038/embor.2012.211

 

A05: Force as a single molecule probe of multidimensional protein energy landscapes.
^{Zoldák Gabriel, Rief Matthias}
Curr Opin Struct Biol. 2013 Feb 
doi: 10.1016/j.sbi.2012.11.007

 

B03/A09: Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 30-splice site recognition.
^{Zhang Yun, Madl Tobias, Bagdiul Ivona, Kern Thomas, Kang Hyun-Seo, Zou Peijian, Mäusbacher Nina, Sieber Stephan A., Krämer Angela, Sattler Michael}
Nucleic Acids Res. 2013 Jan 
doi: 10.1093/nar/gks1097