Publikationen des SFB1035 von 2014

B03: Detection of hydrogen bonds in dynamic regions of RNA by NMR spectroscopy.
^{Dallmann Andre, Sattler Michael}
Curr Protoc Nucleic Acid Chem. 2014 Dec 12
doi: 10.1002/0471142700.nc0722s59

A07: The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.
^{Schuch Benjamin, Feigenbutz Monika, Makino Debora L., Falk Sebastian, Basquin Claire, Mitchell Phil, Conti Elena}
EMBO J. 2014 Dec 1
doi: 10.15252/embj.201488757

B02: Hamiltonian replica exchange combined with elastic network analysis to enhance global domain motions in atomistic molecular dynamics simulations.
^{Ostermeir Katja, Zacharias Martin}
Proteins. 2014 Dec
doi: 10.1002/prot.24695

A03: Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop.
^{Alvira Sara, Cuéllar Jorge , Röhl Alina, Yamamoto Soh, Itoh Hideaki, Alfonso Carlos, Rivas Germán, Buchner Johannes, Valpuesta José M.}
Nat Commun. 2014 Nov 19
doi: 10.1038/ncomms6484

B03: Structural basis for the assembly of the Sxl-Unr translation regulatory complex.
^{Hennig Janosch, Militti Cristina, Popowicz Grzegorz M., Wang Iren, Sonntag Miriam, Geerlof Arie, Gabel Frank, Gebauer Fátima, Sattler Michael}
Nature. 2014 Nov 13
doi: 10.1038/nature13693

A03: Artificial accelerators of the molecular chaperone Hsp90 facilitate rate-limiting conformational transitions.
^{Zierer Bettina K., Weiwad Matthias, Rübbelke Martin, Freiburger Lee, Fischer Gunter, Lorenz Oliver R., Sattler Michael, Richter Klaus, Buchner Johannes}
Angew Chem Int Ed Engl. 2014 Nov 3
doi: 10.1002/anie.201406578

A02/A09: Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site.
^{Dubiella Christian, Cui Haissi, Gersch Malte, Brouwer Arwin J., Sieber Stephan A., Krüger Achim, Liskamp Rob M. J., Groll Michael}
Angew Chem Int Ed Engl. 2014 Oct 27
doi: 10.1002/anie.201406964

B03: A novel protein-protein interaction in the RES (REtention and Splicing) complex.
^{Tripsianes Konstantinos, Friberg Anders, Barrandon Charlotte, Brooks Mark, van Tilbeurgh Herman, Seraphin Bertrand, Sattler Michael}
J Biol Chem. 2014 Oct 10
doi: 10.1074/jbc.M114.592311

A07: The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities.
^{Falk Sebastian, Weir John R., Hentschel Jendrik, Reichelt Peter, Bonneau Fabien, Conti Elena}
Mol Cell. 2014 Sep 18
doi: 10.1016/j.molcel.2014.07.020

A02: Interactions of the natural product kendomycin and the 20S proteasome.
^{Beck Philipp, Heinemeyer Wolfgang, Späth Anna-Lena, Elnakady Yasser, Müller Rolf, Groll Michael}
J Mol Biol. 2014 Sep 9
doi: 10.1016/j.jmb.2014.06.019

A07: Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6.
^{Chakrabarti Sutapa, Bonneau Fabien, Schüssler Steffen, Eppinger Elfriede, Conti Elena}
Nucleic Acids Res. 2014 Aug
doi: 10.1093/nar/gku578

B07/B09/B03: Site-specific analysis of heteronuclear Overhauser effects in microcrystalline proteins.
^{Lopez del Amo Juan Miguel, Agarwal Vipin, Sarkar Riddhiman, Porter Justin, Asami Sam, Rübbelke Martin, Fink Uwe, Xue Yi, Lange Oliver F., Reif Bernd}
J Biomol NMR. 2014 Aug
doi: 10.1007/s10858-014-9843-1

A07: The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
^{Schäfer Ingmar B., Rode Michaela, Bonneau Fabien, Schüssler Steffen, Conti Elena}
J Nat Struct Mol Biol. 2014 Jul
doi: 10.1038/nsmb.2834

B03: The dynamic duo: combining NMR and small angle scattering in structural biology.
^{Hennig Janosch, Sattler Michael}
Protein Sci. 2014 Jun
doi: 10.1002/pro.2467

B02: Protein-ligand docking using hamiltonian replica exchange simulations with soft core potentials.
^{Luitz Manuel P., Zacharias Martin}
J Chem Inf Model 2014 Jun 23
doi: 10.1021/ci500296f

A07: Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in MicroRNA repression.
^{Mathys Hansruedi, Basquin Jérôme, Özgür Sevim, Czarnocki-Cieciura Mariusz, Bonneau Fabien, Aartse Aafke, Dziembowski Andrzej, Nowotny Marcin, Conti Elena, Filipowicz Witold}
Mol Cell. 2014 Jun 5
doi: 10.1016/j.molcel.2014.03.036

A02/A03: The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
^{Feige Matthias J., Gräwert Melissa A., Marcinowski Moritz, Hennig Janosch, Behnke Julia, Ausländer David, Herold Eva M., Peschek Jirka, Castro Caitlin D., Flajnik Martin, Hendershot Linda M., Sattler Michael, Groll Michael, Buchner Johannes}
Proc Natl Acad Sci USA. 2014 Jun 3
doi: 10.1073/pnas.1321502111

B03: Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
^{Huang Jie-rong, Warner Lisa R., Sanchez Carolina, Gabel Frank, Madl Tobias, Mackereth Cameron D., Sattler Michael, Blackledge Martin}
J Am Chem Soc. 2014 May 14
doi: 10.1021/ja502030n

B03: Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
^{Wang Iren, Hennig Janosch, Jagtap Pravin Kumar Ankush, Sonntag Miriam, Valcarcel Juan, Sattler Michael}
Nucleic Acids Res. 2014 May
doi: 10.1093/nar/gku193

B07: Dynamics in the solid-state: perspectives for the investigation of amyloid aggregates, membrane proteins and soluble protein complexes.
^{Linser Rasmus, Sarkar Riddhiman, Krushelnitzky Alexey, Mainz Andi, Reif Bernd}
J Biomol NMR. 2014 May
doi: 10.1007/s10858-014-9822-6

A11: Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.
^{Abate Carmen, Niso Mauro, Marottoli Roberta, Riganti Chiara, Ghigo Dario, Ferorelli Savina, Ossato Giulia, Perrone Roberto, Lacivita Enza, Lamb Don C., Berardi Francesco}
J Med Chem. 2014 Apr 24
doi: 10.1021/jm401874n

B03: Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy.
^{Schilling Franz, Warner Lisa R., Gershenzon Naum I., Skinner Thomas E., Sattler Michael, Glaser Steffen}
J. Angew Chem Int Ed Engl. 2014 Apr 22
doi: 10.1002/anie.201400178

A01: Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome.
^{Unverdorben Pia, Beck Florian, Sledź Paweł, Schweitzer Andreas, Pfeifer Günter, Plitzko Jürgen M., Baumeister Wolfgang, Förster Friedrich}
Proc Natl Acad Sci USA. 2014 Apr 15
doi: 10.1073/pnas.1403409111

B04: Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the kinase 'Target of Rapamycin' by NMR, oriented CD spectroscopy and MD simulations.
^{Sommer Lisa A. M., Janke J. Joel, Bennett W. F. Drew, Bürck Jochen, Ulrich Anne S., Tieleman D. Peter, Dames Sonja Alexandra}
J Phys Chem B. 2014 Apr 11 7
doi: 10.1021/jp501533d

B04: Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'Target of Rapamycin' by NMR and CD spectroscopy.
^{Sommer Lisa A. M., Dames Sonja Alexandra}
FEBS Lett. 2014 Apr 3
doi: 10.1016/j.febslet.2014.03.031

A03: Modulation of the Hsp90 chaperone cycle by a stringent client protein.
^{Lorenz Oliver Robin, Freiburger Lee, Rutz Daniel Andreas, Krause Maike, Zierer Bettina Karolina, Alvira Sara, Cuellar Jorge, Valpuesta Jose Maria, Madl Tobias, Sattler Michael, Buchner Johannes}
Mol Cell. 2014 Mar 20
doi: 10.1016/j.molcel.2014.02.003

A04: Protein-protein interactions visualized by bimolecular fluorescence complementation in tobacco protoplasts and leaves.
^{Schweiger Regina, Schwenkert Serena}
J Vis Exp. 2014 Mar 9 (85)
doi: 10.3791/51327, Videolink

A01: Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome.
^{Pack Chan-Gi, Yukii Haruka, Toh-e Akio, Kudo Tai, Tsuchiya Hikaru, Kaiho Ai, Sakata Eri, Murata Shigeo, Yokosawa Hideyoshi, Sako Yasushi, Baumeister Wolfgang, Tanaka Keiji, Saeki Yasushi}
Nat Commun. 2014 Mar 6
doi: 10.1038/ncomms4396

B07: NMR studies of small molecules interacting with amyloidogenic proteins.
^{Prade Elke, Lopez del Amo Juan Miguel, Reif Bernd}
in: Separovic Frances, Naito Akira (Eds.) RSC, Cambridge, Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides, Chapter 27 pp 533-555 2014 Mar 6
doi: 10.1039/9781782627449-00533

B06: Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide.
^{Yan Li-Mei, Velkova Aleksandra, Kapurniotu Aphrodite}
Curr Pharm Des. 2014 Mar
doi: 10.2174/13816128113199990064

A01: Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.
^{Pathare Ganesh Ramnath, Nagy István, Sledź Paweł, Anderson Daniel J., Zhou Han-Jie, Pardon Els, Steyaert Jan, Förster Friedrich, Bracher Andreas, Baumeister Wolfgang}
Proc Natl Acad Sci USA. 2014 Feb 25
doi: 10.1073/pnas.1400546111

B03: Studying weak and dynamic interactions of posttranslationally modified proteins using expressed protein ligation.
^{Tripsianes Konstantinos, Chu Nam K., Friberg Anders, Sattler Michael, Becker Christian F. W.}
ACS Chem Biol. 2014 Feb 21
doi: 10.1021/cb400723j

A09/A02: Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition.
^{Gersch Malte, Kolb Roman, Alte Ferdinand, Groll Michael, Sieber Stephan A.}
J Am Chem Soc. 2014 Jan 29
doi: 10.1021/ja4082793

A11: Chaperone action at the single-molecule level.
^{Mashaghi Alireza, Kramer Günter, Lamb Don C., Mayer Matthias P., Tans Sander J.}
Chem Rev. 2014 Jan 8
doi: 10.1021/cr400326k

A02/A09: Omuralide and vibralactone: differences in the proteasome- β-lactone-γ-lactam binding scaffold alter target preferences.
^{List Anja, Zeiler Evelyn, Gallastegui Nerea, Rusch Marion, Hedberg Christian, Sieber Stephan A., Groll Michael}
Angew Chem Int Ed Engl. 2014 Jan 7
doi: 10.1002/anie.201308567

B05: Exploring adenylylation and phosphocholination as post-translational modifications.
^{Müller Matthias P., Albers Michael F., Itzen Aymelt, Hedberg Christian}
Chembiochem. 2014 Jan 3
doi: 10.1002/cbic.201300508