Publikationen des SFB1035 von 2020

B05/B02/B03/A11: Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation.
Savitskiy Sergey, Wachtel Rudolf, Pourjafar-Dehkordi Danial, Kang Hyun-Seo, Trauschke Vanessa, Lamb  Don C., Sattler Michael, Zacharias Martin, Itzen Aymelt
iScience. 2020 Dec 15
doi: 10.1016/j.isci.2020.101940

 

B10: Increasing the chemical space of proteins in living cells via genetic code expansion.
Krauskopf Kristina, Lang Kathrin
Curr Opin Chem Biol. 2020 Oct
doi: 10.1016/j.cbpa.2020.07.012

 

B11: Influence of glycosylation on IL-12 family cytokine biogenesis and function.
Bohnacker Sina, Hildenbrand Karen, Aschenbrenner Isabel, Müller Stephanie I., Esser-von Bieren Julia, Feige Matthias J.
J Mol Immunol 2020 Oct
doi: 10.1016/j.molimm.2020.07.015
 

A03: Hsp90 co-chaperones form plastic genetic networks apted to client maturation.
Biebl Maximilian M., Riedl Maximilian, Buchner Johannes
Cell Rep. 2020 Aug 25
doi: 10.1016/j.celrep.2020.108063
 

A02/B12: Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis.
Bräuer Alois, Zhou  Qiuqin, Grammbitter Gina L. C., Schmalhofer Maximilian, Rühl  Michael, Kaila  Ville R. I., Bode  Helge B., Groll Michael
Nat Chem. 2020 Aug
doi: 10.1038/s41557-020-0491-7

A06: Proteinaceous transformers: Structural and functional variability of human sHsps.
Riedl  Mareike, Strauch  Annika, Catici  Dragana A. M., Haslbeck  Martin
Int J Mol Sci. 2020 Jul 30
doi: 10.3390/ijms21155448
 

B06: The human host-defense peptide cathelicidin LL-37 is a nanomolar inhibitor of amyloid self-assembly of islet amyloid polypeptide (IAPP).
Armiento Valentina, Hille Kathleen, Naltsas Denise, Lin Jennifer S., Barron Annelise E., Kapurniotu Aphrodite
Angew Chem Int Ed Engl. 2020 Jul 27
doi: 10.1002/anie.202000148
 

A11/Z1: Determining the stoichiometry of small protein oligomers using steady-state fluorescence anisotropy.
Heckmeier Philipp J., Agam Ganesh, Teese Mark G., Hoyer Maria, Stehle Ralf, Lamb Don C., Langosch Dieter
Biophys J. 2020 Jul 7
doi: 10.1016/j.bpj.2020.05.025
 

B05: Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.
Gülen Burak, Rosselin Marie, Fauser Joel, Albers Michael F. , Pett Christian, Krisp Christoph, Pogenberg Vivian, Schlüter Hartmut, Hedberg Christian, Itzen Aymelt
Nat Chem. 2020 Jul 6
doi: 10.1038/s41557-020-0484-6
 

B05/A02: Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination.
Ernst Stefan, Ecker Felix, Kaspers Marietta S., Ochtrop Philipp, Hedberg Christian, Groll Michael, Itzen Aymelt
Sci Adv. 2020 May 15
doi: 10.1126/sciadv.aaz8041
 

A11: QuanTI-FRET: a framework for quantitative FRET measurements in living cells.
Coullomb Alexis, Bidan Cécile M., Qian Chen, Wehnekamp Fabian, Oddou Christiane, Albigès-Rizo Corinne, Lamb Don C., Dupont Aurélie
Sci Rep. 2020 Apr 16
doi: 10.1038/s41598-020-62924-w
 

B03: An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Kang Hyun-Seo, Sánchez-Rico Carolina, Ebersberger Stefanie, Sutandy F. X. Reymond, Busch Anke, Welte Thomas, Stehle Ralf, Hipp Clara, Schulz Laura, Buchbender Andreas, Zarnack Kathi, König Julian, Sattler Michael
Proc Natl Acad Sci USA. 2020 Mar 31
doi: 10.1073/pnas.1913483117

 

B05/A02/B03: PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72.
Vieweg Sophie, Mulholland Katie, Bräuning Bastian, Kachariya Nitin, Lai Yu-Chiang,  Toth Rachel, Singh Pawan K.,  Volpi Ilaria, Sattler Michael, Groll Michael, Itzen Aymelt, Muq Miratul M. K.
Biochem J. 2020 Mar 30
doi: 10.1042/BCJ20190664
 

B12/A03/Z1: Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90
Mader  Sophie L., Lopez  Abraham, Lawatscheck Jannis, Luo Qi, Rutz Daniel A., Gamiz-Hernandez Ana P., Sattler  Michael, Buchner Johannes, Kaila Ville R. I.
Nat Commun. 2020 Mar 16
doi: 10.1038/s41467-020-15050-0
 

A03/B12/B10: A methylated lysine is a switch point for conformational communication in the chaperone Hsp90
Rehn Alexandra, Lawatscheck Jannis, Jokisch Marie-Lena, Mader Sophie L., Luo Qi, Tippel Franziska, Blank Birgit , Richter Klaus, Lang Kathrin, Kaila Ville R.I. , Buchner Johannes
Nat Commun. 2020 Mar 5
doi: 10.1038/s41467-020-15048-8
 

B05/B03: Conformational control of small GTPases by AMPylation.
Barthelmes Katja, Ramcke Evelyn, Kang Hyun-Seo, Sattler Michael, Itzen Aymelt
Proc Natl Acad Sci USA. 2020 Mar 2
doi: 10.1073/pnas.1917549117
 

B06: Peptide-based molecular strategies to interfere with protein misfolding, aggregation, and cell degeneration.
Armiento Valentina, Spanopoulou Anna, Kapurniotu Aphrodite
Angew Chem Int Ed Engl. 2020 Feb 24
doi: 10.1002/anie.201906908


B11/B10: Site-specific protein labeling with fluorophores as a tool to monitor protein turnover.
Mideksa Yonatan, Fottner Maximilian, Braus Sebastian, Weiß Caroline, Nguyen Tuan-Anh, Meier Susanne, Lang Kathrin, Feige Matthias J.
Chembiochem. 2020 Feb 3
doi: 10.1002/cbic.201900651


B06: The human cathelicidin LL-37 is a nanomolar inhibitor of amyloid self-assembly of islet amyloid polypeptide (IAPP).
Armiento Valentina, Hille Kathleen, Naltsas Denise, Lin Jennifer S., Barron Annelise E., Kapurniotu Aphrodite
Angew Chem Int Ed Engl. 2020 Jan 30
doi: 10.1002/anie.202000148
 

A09/A10: Acyldepsipeptide probes facilitate specific detection of caseinolytic protease P independent of its oligomeric and activity state.
Eyermann Barbara, Meixner Maximilian, Brötz-Oesterhelt Heike, Antes Iris, Sieber Stephan A.
Chembiochem. 2020 Jan 15
doi: 10.1002/cbic.201900477
 

B13/A06: Quantifying the insertion of membrane proteins into lipid bilayer nanodiscs using a fusion protein strategy.
Häusler Elisabeth  Fredriksson Kai, Goba Inguna, Peters Carsten, Raltchev Kolio, Sperl Laura, Steiner Andrea, Weinkauf Sevil, Hagn Franz
Biochim Biophys Acta Biomembr. 2020 Jan 11
doi: 10.1016/j.bbamem.2020.183190
 

A06: Regulation of small heat-shock proteins by hetero-oligomer formation.
Mymrikov Evgeny V., Riedl Mareike, Peters Carsten, Weinkauf Sevil, Haslbeck Martin, Buchner Johannes
J Biol Chem. 2020 Jan 3
doi: 10.1074/jbc.RA119.011143


A04: The ER luminal C-terminus of AtSec62 is critical for male fertility and plant growth in Arabidopsis thaliana.
Mitterreiter Melanie Jasmine, Bosch Franziska Annamaria, Brylok Thomas, Schwenkert Serena
Plant J. 2020 Jan
doi: 10.1111/tpj.14483